Normal blood clotting occurs through a cascade reaction involving 12 blood factors (commonly referred to as Factor VII, Factor V, Factor II, Factor XII, etc.). This reaction is activated when there is an injured tissue or blood vessel, with the final purpose of forming a clot that patches the lesion and stops the bleeding.

Blood clotting tests are requested to verify existing blood clotting disorders and also as part of preoperative tests before surgery to rule out the presence of a disease that could cause serious complications during surgery.

Coagulation tests are very important in the monitoring and control of patients on anticoagulant therapy.